Dr. Mugler’s research focuses on the development and optimization of magnetic resonance imaging techniques, particularly those for rapid and three-dimensional imaging, drawing on a variety of physics and engineering principles, with a strong emphasis on theoretical modeling and simulation and on practical implementation and evaluation. Currently, his major focuses include high-resolution 3-D imaging of the brain using conventional proton-based methods and imaging and spectroscopy of the lung using hyperpolarized helium- and xenon-based methods.